SINGLE-CELL SEQUENCING
Resolve biology at
single-cell resolution
1,000+
Publications citing Admera’s services
8
Single-cell services
4
Platform Certifications
3 week
Typical Turnaround for Library Preparation & Sequencing
CERTIFIED PROVIDER
Annual Recertifications
FIND THE SINGLE-CELL SOLUTION FOR YOUR RESEARCH
Not sure which assay is right?
Answer 3 quick questions and we’ll match you to the ideal platform for your research.
OUR SERVICES & SOLUTIONS
8 Single-Cell Solutions We Offer
Every platform is run on validated, QC-checked workflows. Certified status means reproducible results and confidence from leading technology innovators.
10x Chromium 3’ / 5’ Gene Expression
The most widely validated single-cell RNA-seq platform. Ideal for cell type discovery, trajectory analysis, and differential gene expression across large cohorts.
Cells per run
Sample Types
Typical TAT
500-10,000+
Fresh cells or nuclei
~ 3 weeks
10x Chromium Multiome (RNA + ATAC)
Gene expression and chromatin accessibility from the same nucleus. Ideal for epigenetic regulation, transcription factor activity, and gene regulatory network analysis.
Modalities
Sample Types
Typical TAT
scRNA + scATAC
Fresh, cryo nuclei, frozen tissue
~ 3 weeks
10x Immune Profiling (VDJ)
Full-length V(D)J sequencing for T and B cell receptor repertoires, paired with gene expression. Ideal for immuno-oncology, autoimmune, and vaccine studies.
Receptor Types
Sample Types
Typical TAT
TCR α/β, BCR H/L
Fresh frozen
~ 3-4 weeks
Illumina Single-cell 3’ RNA Prep
Emulsion-based workflow. Scalable with simplified workflow, ideal for high-throughput gene expression profiling across diverse cell populations.
Captured cells
Sample Types
Typical TAT
Up to 100k
Cells, nuclei
~ 3-4 weeks
10x Chromium Flex Apex (formerly GEM-X Flex V2)
Probe-based chemistry for fixed cells ships at room temperature, multiplexes up to 16 samples per run. Ideal for time-course studies and low-viability specimens.
Captured cells
Sample Types
Typical TAT
up to 1M*
Fresh, frozen, fixed, FFPE
~ 3-4 weeks
(Mini, Mega, Penta)
Parse Biosciences Evercode WT
Combinatorial barcoding — no microfluidics required. Highly scalable (millions of cells), compatible with fixed cells, and cost-effective for large cohorts.
Throughput
Sample Types
Typical TAT
Up to 5M+ cells
Fixed cells, nuclei
~ 3-4 weeks
Takara Shasta Single Cell System
Map gene expression to tissue coordinates. Preserves spatial context critical for tumor microenvironment, brain atlas, and developmental biology studies.
Coverage
Best for
Typical TAT
Full-length transcript
Rare cells, isoforms
~ 3-4 weeks
Singleron GEXSCOPE
Map gene expression to tissue coordinates. Preserves spatial context critical for tumor microenvironment, brain atlas, and developmental biology studies.
Cells per run
Sample Types
Typical TAT
200 - 10,000
Fresh cells, blood
~ 3-4 weeks
COMPATIBILITY
Which platform fits your sample?
Check your sample type against our full platform matrix before submitting a quote request.
What are features of each platform?
Compare key capabilities and find the best match for your workflow.
WORKFLOW
Admera Health offers a highly personalized, client-focused approach to every project, ensuring exceptional data quality and rapid turnaround times. Our commitment to 1:1 support guarantees prompt responses within 24 hours, while our utilization of state-of-the-art technology and rigorous quality control measures ensures the delivery of cutting-edge, high-resolution results.
From sample to publication-ready data
Figure 1. Overview of the General Single-Cell Sequencing Workflow.A. Sample preparation, starting from tissue or cell samples, includes tissue dissociation, single-cell isolation, cell viability assessment. B. Library preparation from a choice of diverse technologies. C. Sequencing is performed on Illumina, Ultima Genomics, or Complete Genomics platforms. D. Following sequencing, Admera Health team performs comprehensive bioinformatic analysis via Admera Health pipelines or vendor software.
RESEARCHER TESTIMONIALS
Admera Health provides comprehensive support for all projects, and delivers publication-ready data. Discover how researchers are using single-cell solutions at Admera Health to advance their studies.
Trusted by labs across institutions
1,000+
Over 500+ peer-reviewed publications cite Admera Health single-cell services from Nature Neuroscience and Cell to Nature Methods and Science Advances.
“We are a functional genomics lab at Duke University that generates both standard and in-house designed NGS libraries, often built on our newly developed technologies and protocols. Sequencing these libraries often requires tailored NGS strategies, and finding the right NGS provider used to be a challenge - until we partnered with Admera Health. Their expertise in NGS is truly outstanding, covering multiple commercial NGS platforms and the latest technologies. Their deep scientific and technical knowledge allows us to have productive discussions to optimize our sequencing approaches at no extra cost. The turnaround time is also remarkable - often just three days or even over a weekend - and their pricing is highly competitive. Admera has exceeded our expectations, and we always recommend their services to collaborators. We looks forward to continuing our partnership in the future.”
“Admera Health’s exceptional quality of service has been a game-changer for our company. As a leader in AI drug discovery, we require high-quality data with an extremely quick turnaround, and Admera consistently delivers, exceeding our expectations every time.
Their single-cell sequencing projects have been instrumental in enabling us to build a massive single-cell profile dataset. This foundational work, fueled by Admera’s reliable and fast data generation, has been crucial in advancing our pipeline and allowing us to train advanced AI models for our virtual cell platforms”
“Our group recently transitioned from in-house sequencing to outsourcing, and the experience has been seamless. We greatly value their quick turnaround time. Their flexibility in accommodating our specific needs and workflows has been invaluable, making the adjustment from in-house operations effortless. On top of that, their highly competitive pricing has made the switch not only easy but also a finanfially attractive decision. Partnering with Admera has been a game-changer for our sequencing needs, and we couldn’t be more pleased with their exceptional service.”
GETTING STARTED
Find answers to our most common inquiries regarding sample requirements, platform selection, turnaround time, pricing, and more.
Frequently asked questions
Sample Preparation & Requirements
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We offer a range of solutions designed to meet your needs—whether you're just getting started or scaling something bigger. Everything is tailored to help you move forward with clarity and confidence.
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To ensure high-quality data, we assess samples based on cell viability for best results, concentration, volume, total cell count, and RNA quality metrics.
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We offer flexible pricing based on project type and complexity. After an initial conversation, we’ll provide a transparent quote with no hidden costs.
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Submission requirements vary by technology.
10x Genomics: High-concentration suspensions for microfluidic capture.
Parse Biosciences: Flexible input for combinatorial barcoding.
Takara: Optimized for low-input or full-length transcript needs.
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Yes, we have specialized protocols for low-input samples. Please consult with our technical team to optimize the recovery strategy for your specific project.
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If viability is low, we can perform dead-cell removal or pivot to a single-nucleus RNA-seq (snRNA-seq) workflow. This workflow is more robust for compromised or frozen samples.
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Getting started is simple. Reach out through our contact form or schedule a call—we’ll walk you through the next steps and answer any questions along the way.
Platform Selection
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This depends on your sample type, research goals, and project scale. Use our Solution Selector tool above to get a recommendation or contact our team for a consultation.
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To ensure high-quality data, we assess samples based on cell viability for best results, concentration, volume, total cell count, and RNA quality metrics.
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If you are working with fresh or cryopreserved samples, Single-cell RNA-seq (scRNA-seq) is the gold standard because it captures the entire transcriptomic picture from both the nucleus and the cytoplasm. This "whole-cell" approach usually yields the highest gene detection per cell, making it ideal for liquid samples like blood or easily dissociated fresh tissue. However, because it requires high cell viability, it can be sensitive to the stresses of tissue processing.
Single-nucleus RNA-seq (snRNA-seq) is a powerful tool for archived or difficult-to-dissociate samples, such as frozen brain or heart tissue. By focusing only on the isolated nuclei, this method bypasses the need for live cells and avoids the cellular damage that often occurs during harsh tissue digestion. While you are primarily sequencing nuclear RNA, the biological insights remain highly accurate.
Pricing is generally comparable.
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Yes! For immune cell samples, we offer 10x Chromium 5' Gene Expression + VDJ profiling. This captures full-length V(D)J sequences for T cell receptors (TCR α/β) and B cell receptors (BCR heavy/light chains), paired with gene expression from the same cells. This must be planned at the library prep stage. Contact us before sample submission.
Turnaround Time
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Standard turnaround (from sample receipt to data delivery) is 3-4 weeks. With bioinformatics analysis add-on, it is additional 1-2 weeks.
Planning before sample shipment is crucial to ensuring a project’s success. Contact us for an expert consultation.
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Yes. Rush processing is available for an additional fee. Contact us as early as possible.
Tissue-Specific Questions
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Yes. Tumor samples (solid tumors and liquid biopsies) are commonly processed.
We can handle fresh tumor dissociation, frozen tumor (snRNA-seq), FFPE tumor (10x Flex/Visium), and immune infiltrate profiling (10x 5' + VDJ).
Tumor samples often have lower viability so we recommend performing dead cell removal or switch to snRNA-seq to bypass viability issues.
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Yes. Brain tissue is one of the most common sample types for single-nucleus RNA-seq. We have extensive experience with cortex, hippocampus, spinal cord, and other CNS tissues across mouse, rat, and human samples. Fresh brain can be dissociated but snRNA-seq from frozen tissue is often preferred to avoid dissociation stress.
Contact us as early as possible.
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Yes. Organoids such as brain, intestinal, liver, etc. are compatible with our workflows. We have worked with dissociated organoid, intact organoid sections, and fixed organoids.
Contact us for guidance on optimal dissociation methods.
Pricing & Costs
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Our standard pricing includes project consultation, sample QC and processing, library preparation, sequencing to the appropriate depth for your platform, and sequencing data in fastq format. Qc reports are delivered within 24-48 hours of sample receipt.
Bioinformatics analysis is available as an optional add-on.
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Yes. Contact our team for a custom quote based on your project size and platform requirements.
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Absolutely. If you've already prepared your single-cell libraries in-house, we offer sequencing-only services. Just provide your libraries at the appropriate concentration and we'll handle sequencing and data delivery.
Contact our team to get started.
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Standard analysis (included as add-on option):
• Quality control and filtering
• Dimensionality reduction (PCA, UMAP/tSNE)
• Cell clustering and annotation
• Differential gene expression analysis
• Publication-ready visualizations
Advanced analysis (custom pricing): Trajectory analysis, cell-cell interactions, multi-dataset integration, gene regulatory networks, and custom workflows.Contact us to receive a formal quote.
Not sure where to start?
Talk to one of our scientists.
A free 30-minute project consultation with a PhD-level scientist. We'll help you pick the right platform, flag sample prep considerations, and estimate costs before you commit to anything.
Sending samples?
See our single cell sample submission guideline for sample preparation, packing, and shipping instructions.